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Encapsulated Thermoacoustic Projector Based on Free-Standing Carbon Nanotube Film
Technical Summary: There are promising applications for thermophones in high power sonar arrays, flexible loudspeakers, and noise cancellation devices. Transparent CNT sheets have the density of air, the electrical conductivity of metals, and the flexibility to fit to any curved surface. Thermoacoustic (TA) sound generation results from temperature...
Published: 11/3/2020   |   Inventor(s): Ali Aliev, Ray Baughman
Keywords(s): Communications, Devices, Electronics, Engineering & Physical Sciences, Materials
Category(s): Electronics
Volume-Filler Universal Sample Holder for Critical Point Dryers
Critical Point Dryers (CPD) require strict adherence to operation guidelines to minimize accumulation of foreign particles, but there are still some that accrue during regular use. Particles build-up over time and may become trapped within the CPD, leading to consistent particle contamination of samples despite carefully cleaning the machine. While...
Published: 5/20/2020   |   Inventor(s): Roger Robbins
Keywords(s): Engineering & Physical Sciences, Materials, Research Tools
Category(s): Devices
Multiplexed Chip System for Analysis of Drug Activity in Cell Extracts
This technology uses multielectrode chips with DNA monolayers to analyze drug activity of DNA-damaging cancer treatments to inform therapeutic decisions for personalized medicine. Due to the unpredictability of cancer drugs, it is difficult to identify which therapy will work most effectively for each individual while producing minimal side effects....
Published: 4/26/2019   |   Inventor(s): Jason Slinker, Dimithree Kahanda, David Boothman
Keywords(s): Assay, Biomarkers, Cell Lines, Devices, Engineering & Physical Sciences, Materials, Medical, Membrane, Microfluidics, Processes, Therapeutics
Category(s): Electronics, Diagnostics, Healthcare, Research Tools
Transient Optical Opening of the Blood-Brain Barrier by Laser Excitation of Plasmonic Nanoparticles
The blood-brain barrier (BBB) poses a low permeability to most drugs and poses a significant challenge to effective treatment of brain diseases. The BBB restricts the delivery of most drug molecules into the brain by tight junctions (TJs) that seal gaps between adjacent endothelial cells, displaying low permeability and high electrical resistance. Herein,...
Published: 4/26/2019   |   Inventor(s): Zhenpeng Qin, Xiaoqing Li, Xiuying Li, Shashank Sirsi, Heather Hayenga, Edward Pan
Keywords(s): Biomarkers, Diagnostics, Drug Delivery, Engineering & Physical Sciences, Imaging, Materials, Medical, Research Tools, Therapeutics
Category(s): Biomedical, Nanotechnology, Healthcare
Amorphous Silicon Carbide Ultramicroelectrode Arrays for Neural Interfaces
The clinical ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response (FBR), which can lead to neuron damage and reduced reliability. Minimizing this tissue response is necessary for the development of implantable interfaces for studying neural...
Published: 4/26/2019   |   Inventor(s): Stuart Cogan, Timothy Gardner
Keywords(s): Biocompatible, Electronics, Engineering & Physical Sciences, Implantable, Life Sciences, Materials, Medical, Sensors & Controls, Therapeutics
Category(s): Research Tools, Devices, Healthcare
Neurocase: Peripheral Nerve Electrode for Neural Recording and Stimulation
The ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response, which can lead to neuron damage and reduced reliability of results. Minimizing such tissue responses is necessary to develop implantable interfaces for studying neural activity and even...
Published: 1/5/2022   |   Inventor(s): Stuart Cogan, Atefeh Ghazavi, Alexandra Joshi-Imre
Keywords(s): Biocompatible, Biotechnology, Electronics, Engineering & Physical Sciences, Healthcare, Implantable, Life Sciences, Materials, Medical, Medical Devices, Therapeutics
Category(s): Biomedical, Devices, Research Tools
Method for Measuring Carbon Nanotubes Taken-Up by a Plurality of Living Cells
Carbon nanomaterials (CNMs), including carbon nanotubes (CNTs) and graphene, are undergoing extensive research due to their diverse commercial applications and potential for biomedical uses. The global increase in the production of CNMs and incorporation into consumer products is cause for concern because of the consistent reports that CNMs can be toxic....
Published: 4/26/2019   |   Inventor(s): Rockford Draper, Paul Pantano, Ru-Hung Wang, Carole Mikoryak
Keywords(s): Assay, Biotechnology, Carbon Nanomaterials, Carbon Nanotubes, Engineering & Physical Sciences, Healthcare, Imaging, Life Sciences, Materials, Microfluidics, Molecular Biology, Nanotechnology, Processes
Category(s): Research Tools
Multifunctional Ionic liquids for Surface Modification of Dental Implants
Titanium dental implants are known for their high success rates and adequate osseointegration in vivo. However, with an increasing number of implants used, higher incidence of failures has been reported. These failures have been associated with microbial colonization, peri-implant inflammation, corrosion, implant design, overload, as well as a combination...
Published: 4/26/2019   |   Inventor(s): Danieli Rodrigues, Izabelle De Mello Gindri
Keywords(s): Antibodies, Biocompatible, Biomaterials, Coatings, Drug Delivery, Healthcare, Implantable, Life Sciences, Materials, Medical, Medical Devices, Therapeutics
Category(s): Biomedical, Dental
Novel Class of pH Responsive and Renal Clearable Tumor Imaging Agents
Non-Confidential Description:The technology is a novel class of pH responsive luminescent gold nanoparticles that are renal clearable and that selectively bind to cells in an acidic environment such as tumor cells. An advantage of these novel pH responsive nanoparticles is that they can be used to specifically target the acidic microenvironment of tumor...
Published: 4/23/2021   |   Inventor(s): Jie Zheng
Keywords(s): Biocompatible, Biomarkers, Biomaterials, Diagnostics, Healthcare, Imaging, Life Sciences, Materials, Medical, Nanotechnology, Research Tools, Therapeutics
Category(s): Biomedical, Imaging
Novel Nitric Oxide Releasing Surgical Sutures, Bandages and Fabrics
Non-Confidential DescriptionThe technology is novel nitric oxide (NO) releasing acrylonitrile-based copolymer and terpolymer fibers that can be used as surgical sutures or non-woven bandages and fabrics that enhance wound healing. These copolymers have a higher NO loading capacity per gram than other known NO releasing acrylonitrile polymers. In addition,...
Published: 4/26/2019   |   Inventor(s): Kenneth Balkus, Alysia Lowe, Dennis Smith, Wenjin Deng
Keywords(s): Biocompatible, Drug Delivery, Healthcare, Life Sciences, Materials, Medical, Medical Devices, Polymers, Textiles, Therapeutics
Category(s): Healthcare
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