Description:
Titanium dental implants are known for their high success rates and adequate osseointegration in vivo. However, with an increasing number of implants used, higher incidence of failures has been reported. These failures have been associated with microbial colonization, peri-implant inflammation, corrosion, implant design, overload, as well as a combination of multiple factors. Ionic liquids (ILs) constitute a versatile class of materials in which modifications in cationic and anionic moieties can be performed to obtain compounds with specific properties. Non-toxic and multifunctional imidazolium-based IL coatings for dental implant surfaces have been designed. Recent studies demonstrated that IL compounds functionalized with dicationic moieties and organic anions induced antimicrobial activity against bacteria relevant to the oral environment while enabling differentiation of pre-osteoblast cells into osteoblasts. Select IL formulations also were reported to form stable films on the surface of titanium with high adhesion strength, providing improved lubrication and corrosion protection, which are useful properties to assist with implant insertion and preservation of the oxide layer during the initial healing period.
Applications
• Dental implants
Benefits
• Functionalization of titanium surfaces with antimicrobial, anticorrosive and lubricant activities
Patent Status: Patent pending.
Licensing Status: This technology is available for exclusive or non-exclusive licensing.
Contact: otc@utdallas.edu
ID Number: 14018