Search Results - therapeutics

21 Results Sort By:
Hardware and Software System for At-Home Stereognosis Training
Sensory loss of the hand (including impaired proprioception, stereognosis, and tactile sensation) is common after peripheral nerve damage, stroke, spinal cord injury, multiple sclerosis (MS), and other neurological conditions. While sensory retraining therapy has shown some benefits, there is no established method to restore tactile sensation following...
Published: 1/5/2022   |   Inventor(s): Michael Kilgard
Keywords(s): Devices, Engineering & Physical Sciences, Internet of Things (IoT), Medical, Research Tools, Software, Therapeutics, Wireless
Category(s): Diagnostics, Healthcare, Medical Devices
Multiplexed Chip System for Analysis of Drug Activity in Cell Extracts
This technology uses multielectrode chips with DNA monolayers to analyze drug activity of DNA-damaging cancer treatments to inform therapeutic decisions for personalized medicine. Due to the unpredictability of cancer drugs, it is difficult to identify which therapy will work most effectively for each individual while producing minimal side effects....
Published: 4/26/2019   |   Inventor(s): Jason Slinker, Dimithree Kahanda, David Boothman
Keywords(s): Assay, Biomarkers, Cell Lines, Devices, Engineering & Physical Sciences, Materials, Medical, Membrane, Microfluidics, Processes, Therapeutics
Category(s): Electronics, Diagnostics, Healthcare, Research Tools
Desensitization and Reduction of Chronic Pain
The University of Texas at Dallas presents a novel class of inhibitors, specificity-derived competitive inhibitor oligonucleotides (SPOT-ONs) that bind to poly(A) binding protein (PABP), and the associated inventive strategy to treat pathological pain. Pathological pain plasticity has been shown to take place in nociceptors, sensory neurons which...
Published: 4/26/2019   |   Inventor(s):  
Keywords(s): Chemistry, Diagnostics, Healthcare, Life Sciences, Molecular Biology, Therapeutics
Category(s): Research Tools
Total Energy Shaping for Task-Invariant Control of Lower-Limb Exoskeletons
We present a total energy shaping control methodology for the development of portable lower-limb assistive exoskeletons and orthotic devices that help reduce the human’s effort and augment natural motion. Current robotic exoskeletons restrict joint motion to pre-defined position trajectories during gait rehabilitation; such methods aim to replicate...
Published: 5/20/2020   |   Inventor(s): Robert Gregg, Ge Lv
Keywords(s): Biocompatible, Devices, Electronics, Engineering & Physical Sciences, Mechanical Systems, Medical Devices, Research Tools, Sensors & Controls, Signal Processing, Software, Therapeutics, Transportation, Wireless
Category(s): Robotics, Healthcare, Control Strategy
A Lower Limb Powered Orthosis for Improved Rehabilitation Training
Physical training is often needed for patients to relearn how to walk after a stroke, or other neurological damage. However, the frequency and availability of physical training are limited by finite medical resources: most lower-limb rehabilitation orthoses are stationary and only available in a limited number of clinical settings, due to their large...
Published: 5/20/2020   |   Inventor(s): Robert Gregg, Hanqi Zhu
Keywords(s): Electronics, Engineering & Physical Sciences, Medical Devices, Motors, Research Tools, Sensors & Controls, Therapeutics
Category(s): Devices, Healthcare, Robotics, Mechanical Systems
Transient Optical Opening of the Blood-Brain Barrier by Laser Excitation of Plasmonic Nanoparticles
The blood-brain barrier (BBB) poses a low permeability to most drugs and poses a significant challenge to effective treatment of brain diseases. The BBB restricts the delivery of most drug molecules into the brain by tight junctions (TJs) that seal gaps between adjacent endothelial cells, displaying low permeability and high electrical resistance. Herein,...
Published: 4/26/2019   |   Inventor(s): Zhenpeng Qin, Xiaoqing Li, Xiuying Li, Shashank Sirsi, Heather Hayenga, Edward Pan
Keywords(s): Biomarkers, Diagnostics, Drug Delivery, Engineering & Physical Sciences, Imaging, Materials, Medical, Research Tools, Therapeutics
Category(s): Biomedical, Nanotechnology, Healthcare
Novel Aconitase: Targeting Phenotypic Adaptation for Antimicrobial Development
Worldwide, bacterial pathogens pose an alarming public health threat due to their resistance to current antimicrobial drugs. While antibiotics have been widely used to prevent bacterial infections over the last 50-60 years, all major bacterial pathogens now are showing resistance to currently prescribed antibiotics worldwide. Increasing drug resistance...
Published: 4/26/2019   |   Inventor(s): Mehmet Candas, Lee Bulla
Keywords(s): Antibiotics, Biomarkers, Life Sciences, Medical, Molecular Biology, Therapeutics
Category(s): Healthcare, Research Tools
Virtual Body-Weight Support via Lower-Limb Exoskeleton
Summary:This is a novel control system for powered lower-limb exoskeletons (or orthoses) that provides body-weight support (BWS) for people who have sustained a stroke and other neurological injury. Patients are provided with BWS during conventional gait retraining to help them produce the coordinated muscle activities needed for walking. Although current...
Published: 5/20/2020   |   Inventor(s): Robert Gregg, Ge Lv, Hanqi Zhu
Keywords(s): Biotechnology, Engineering & Physical Sciences, Life Sciences, Medical Devices, Motors, Research Tools, Sensors & Controls, Signal Processing, Therapeutics
Category(s): Electronics, Healthcare, Robotics, Control Strategy, Devices, Mechanical Systems
Amorphous Silicon Carbide Ultramicroelectrode Arrays for Neural Interfaces
The clinical ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response (FBR), which can lead to neuron damage and reduced reliability. Minimizing this tissue response is necessary for the development of implantable interfaces for studying neural...
Published: 4/26/2019   |   Inventor(s): Stuart Cogan, Timothy Gardner
Keywords(s): Biocompatible, Electronics, Engineering & Physical Sciences, Implantable, Life Sciences, Materials, Medical, Sensors & Controls, Therapeutics
Category(s): Research Tools, Devices, Healthcare
Neurocase: Peripheral Nerve Electrode for Neural Recording and Stimulation
The ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response, which can lead to neuron damage and reduced reliability of results. Minimizing such tissue responses is necessary to develop implantable interfaces for studying neural activity and even...
Published: 1/5/2022   |   Inventor(s): Stuart Cogan, Atefeh Ghazavi, Alexandra Joshi-Imre
Keywords(s): Biocompatible, Biotechnology, Electronics, Engineering & Physical Sciences, Healthcare, Implantable, Life Sciences, Materials, Medical, Medical Devices, Therapeutics
Category(s): Biomedical, Devices, Research Tools
1 2 3 
© 2024. All Rights Reserved. Powered by Inteum