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Volume-Filler Universal Sample Holder for Critical Point Dryers

Critical Point Dryers (CPD) require strict adherence to operation guidelines to minimize accumulation of foreign particles, but there are still some that accrue during regular use. Particles build-up over time and may become trapped within the CPD, leading to consistent particle contamination of samples despite carefully cleaning the machine. While...

Published: 5/20/2020 | Inventor(s): Roger Robbins

Keywords(s): Engineering & Physical Sciences, Materials, Research Tools

Category(s): Devices

System for Extracting Venous Pulsation and Respiratory Information from Photoplethysmographs

The University of Texas at Dallas presents a technique that addresses the inaccuracy of skin-mounted photoplethysmographic (PPG) biosensor measurements by separating the arterial and venous signals - enabling extraction of other medically-relevant features, including: respiration rate, heart rate, and SpO2. The effective removal of various motion artifacts...

Published: 4/26/2019 | Inventor(s): Mehrdad Nourani, Rasoul Yousefi

Keywords(s): 5G, Assay, Diagnostics, Electronics, Research Tools, Software, Wireless

Category(s): Healthcare, Software & Information Technology, Signal Processing, Medical Devices

Accurate and Motion-Tolerant Sensing of Arterial and Venous Pulsation for Wearable Photoplethysmographic (PPG) Biosensors

The University of Texas at Dallas presents a real-time, adaptive technique that provides robust signal enhancement against motion artifact for wearable photoplethysmographic (PPG) systems, enabling the reliable extraction of heart rate and oxygen saturation. Despite the benefits of using PPG biosensors, most of the useful information they capture...

Published: 4/26/2019 | Inventor(s): Mehrdad Nourani, Rasoul Yousefi

Keywords(s): 5G, Assay, Diagnostics, Electronics, Research Tools, Software, Wireless

Category(s): Healthcare, Medical Devices, Signal Processing, Software & Information Technology

Hardware and Software System for At-Home Stereognosis Training

Sensory loss of the hand (including impaired proprioception, stereognosis, and tactile sensation) is common after peripheral nerve damage, stroke, spinal cord injury, multiple sclerosis (MS), and other neurological conditions. While sensory retraining therapy has shown some benefits, there is no established method to restore tactile sensation following...

Published: 1/5/2022 | Inventor(s): Michael Kilgard

Keywords(s): Devices, Engineering & Physical Sciences, Internet of Things (IoT), Medical, Research Tools, Software, Therapeutics, Wireless

Category(s): Diagnostics, Healthcare, Medical Devices

Total Energy Shaping for Task-Invariant Control of Lower-Limb Exoskeletons

We present a total energy shaping control methodology for the development of portable lower-limb assistive exoskeletons and orthotic devices that help reduce the human’s effort and augment natural motion. Current robotic exoskeletons restrict joint motion to pre-defined position trajectories during gait rehabilitation; such methods aim to replicate...

Published: 5/20/2020 | Inventor(s): Robert Gregg, Ge Lv

Keywords(s): Biocompatible, Devices, Electronics, Engineering & Physical Sciences, Mechanical Systems, Medical Devices, Research Tools, Sensors & Controls, Signal Processing, Software, Therapeutics, Transportation, Wireless

Category(s): Robotics, Healthcare, Control Strategy

A Lower Limb Powered Orthosis for Improved Rehabilitation Training

Physical training is often needed for patients to relearn how to walk after a stroke, or other neurological damage. However, the frequency and availability of physical training are limited by finite medical resources: most lower-limb rehabilitation orthoses are stationary and only available in a limited number of clinical settings, due to their large...

Published: 5/20/2020 | Inventor(s): Robert Gregg, Hanqi Zhu

Keywords(s): Electronics, Engineering & Physical Sciences, Medical Devices, Motors, Research Tools, Sensors & Controls, Therapeutics

Category(s): Devices, Healthcare, Robotics, Mechanical Systems

Transient Optical Opening of the Blood-Brain Barrier by Laser Excitation of Plasmonic Nanoparticles

The blood-brain barrier (BBB) poses a low permeability to most drugs and poses a significant challenge to effective treatment of brain diseases. The BBB restricts the delivery of most drug molecules into the brain by tight junctions (TJs) that seal gaps between adjacent endothelial cells, displaying low permeability and high electrical resistance. Herein,...

Published: 4/26/2019 | Inventor(s): Zhenpeng Qin, Xiaoqing Li, Xiuying Li, Shashank Sirsi, Heather Hayenga, Edward Pan

Keywords(s): Biomarkers, Diagnostics, Drug Delivery, Engineering & Physical Sciences, Imaging, Materials, Medical, Research Tools, Therapeutics

Category(s): Biomedical, Nanotechnology, Healthcare

Virtual Body-Weight Support via Lower-Limb Exoskeleton

Summary:This is a novel control system for powered lower-limb exoskeletons (or orthoses) that provides body-weight support (BWS) for people who have sustained a stroke and other neurological injury. Patients are provided with BWS during conventional gait retraining to help them produce the coordinated muscle activities needed for walking. Although current...

Published: 5/20/2020 | Inventor(s): Robert Gregg, Ge Lv, Hanqi Zhu

Keywords(s): Biotechnology, Engineering & Physical Sciences, Life Sciences, Medical Devices, Motors, Research Tools, Sensors & Controls, Signal Processing, Therapeutics

Category(s): Electronics, Healthcare, Robotics, Control Strategy, Devices, Mechanical Systems

Noninvasive & High-Contrast Imaging of Kidney Function Enabled by Renal Clearable Nanofluorophores

The University of Texas at Dallas is seeking companies interested in commercializing a renal-clearable contrast agent that is the first to enable high-resolution, noninvasive, fluorescent imaging of kidney function. Kidney disease affects more than 10% of adults worldwide and the current technologies used to detect and track the progress of renal complications...

Published: 4/26/2019 | Inventor(s): Jie Zheng, Mengxiao Yu

Keywords(s): Biocompatible, Biomarkers, Chemistry, Diagnostics, Healthcare, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools

Category(s): Biomedical, Imaging

Small Molecule Inhibitor of Forkhead Box Protein C2 (FOXC2): Therapeutic Candidate and Diagnostic Tool for Metastatic Cancers

The transcription factor Forkhead Box Protein C2 (FOXC2) is known to be necessary to initiate and maintain the epithelial-mesenchymal transition (EMT), which has been a hot target for therapeutic intervention against cancers. The overexpression of FOXC2 bestows cancer cells with metastatic and cancer stem cell (CSC)‐like phenotypes, i.e., higher motility,...

Published: 4/26/2019 | Inventor(s): Jiyong Lee, Maria Castaneda

Keywords(s): Assay, Biocompatible, Biomarkers, Chemistry, Drug Delivery, Healthcare, Imaging, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools, Therapeutics

Category(s): Biomedical, Diagnostics

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