Search Results - diagnostics

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System for Extracting Venous Pulsation and Respiratory Information from Photoplethysmographs

The University of Texas at Dallas presents a technique that addresses the inaccuracy of skin-mounted photoplethysmographic (PPG) biosensor measurements by separating the arterial and venous signals - enabling extraction of other medically-relevant features, including: respiration rate, heart rate, and SpO2. The effective removal of various motion artifacts...

Published: 4/26/2019 | Inventor(s): Mehrdad Nourani, Rasoul Yousefi

Keywords(s): 5G, Assay, Diagnostics, Electronics, Research Tools, Software, Wireless

Category(s): Healthcare, Software & Information Technology, Signal Processing, Medical Devices

Accurate and Motion-Tolerant Sensing of Arterial and Venous Pulsation for Wearable Photoplethysmographic (PPG) Biosensors

The University of Texas at Dallas presents a real-time, adaptive technique that provides robust signal enhancement against motion artifact for wearable photoplethysmographic (PPG) systems, enabling the reliable extraction of heart rate and oxygen saturation. Despite the benefits of using PPG biosensors, most of the useful information they capture...

Published: 4/26/2019 | Inventor(s): Mehrdad Nourani, Rasoul Yousefi

Keywords(s): 5G, Assay, Diagnostics, Electronics, Research Tools, Software, Wireless

Category(s): Healthcare, Medical Devices, Signal Processing, Software & Information Technology

Desensitization and Reduction of Chronic Pain

The University of Texas at Dallas presents a novel class of inhibitors, specificity-derived competitive inhibitor oligonucleotides (SPOT-ONs) that bind to poly(A) binding protein (PABP), and the associated inventive strategy to treat pathological pain. Pathological pain plasticity has been shown to take place in nociceptors, sensory neurons which...

Published: 4/26/2019 | Inventor(s):

Keywords(s): Chemistry, Diagnostics, Healthcare, Life Sciences, Molecular Biology, Therapeutics

Category(s): Research Tools

Transient Optical Opening of the Blood-Brain Barrier by Laser Excitation of Plasmonic Nanoparticles

The blood-brain barrier (BBB) poses a low permeability to most drugs and poses a significant challenge to effective treatment of brain diseases. The BBB restricts the delivery of most drug molecules into the brain by tight junctions (TJs) that seal gaps between adjacent endothelial cells, displaying low permeability and high electrical resistance. Herein,...

Published: 4/26/2019 | Inventor(s): Zhenpeng Qin, Xiaoqing Li, Xiuying Li, Shashank Sirsi, Heather Hayenga, Edward Pan

Keywords(s): Biomarkers, Diagnostics, Drug Delivery, Engineering & Physical Sciences, Imaging, Materials, Medical, Research Tools, Therapeutics

Category(s): Biomedical, Nanotechnology, Healthcare

Noninvasive & High-Contrast Imaging of Kidney Function Enabled by Renal Clearable Nanofluorophores

The University of Texas at Dallas is seeking companies interested in commercializing a renal-clearable contrast agent that is the first to enable high-resolution, noninvasive, fluorescent imaging of kidney function. Kidney disease affects more than 10% of adults worldwide and the current technologies used to detect and track the progress of renal complications...

Published: 4/26/2019 | Inventor(s): Jie Zheng, Mengxiao Yu

Keywords(s): Biocompatible, Biomarkers, Chemistry, Diagnostics, Healthcare, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools

Category(s): Biomedical, Imaging

Novel Class of pH Responsive and Renal Clearable Tumor Imaging Agents

Non-Confidential Description:The technology is a novel class of pH responsive luminescent gold nanoparticles that are renal clearable and that selectively bind to cells in an acidic environment such as tumor cells. An advantage of these novel pH responsive nanoparticles is that they can be used to specifically target the acidic microenvironment of tumor...

Published: 4/23/2021 | Inventor(s): Jie Zheng

Keywords(s): Biocompatible, Biomarkers, Biomaterials, Diagnostics, Healthcare, Imaging, Life Sciences, Materials, Medical, Nanotechnology, Research Tools, Therapeutics

Category(s): Biomedical, Imaging