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Encapsulated Thermoacoustic Projector Based on Free-Standing Carbon Nanotube Film

Technical Summary: There are promising applications for thermophones in high power sonar arrays, flexible loudspeakers, and noise cancellation devices. Transparent CNT sheets have the density of air, the electrical conductivity of metals, and the flexibility to fit to any curved surface. Thermoacoustic (TA) sound generation results from temperature...

Published: 11/3/2020 | Inventor(s): Ali Aliev, Ray Baughman

Keywords(s): Communications, Devices, Electronics, Engineering & Physical Sciences, Materials

Category(s): Electronics

Volume-Filler Universal Sample Holder for Critical Point Dryers

Critical Point Dryers (CPD) require strict adherence to operation guidelines to minimize accumulation of foreign particles, but there are still some that accrue during regular use. Particles build-up over time and may become trapped within the CPD, leading to consistent particle contamination of samples despite carefully cleaning the machine. While...

Published: 5/20/2020 | Inventor(s): Roger Robbins

Keywords(s): Engineering & Physical Sciences, Materials, Research Tools

Category(s): Devices

Hardware and Software System for At-Home Stereognosis Training

Sensory loss of the hand (including impaired proprioception, stereognosis, and tactile sensation) is common after peripheral nerve damage, stroke, spinal cord injury, multiple sclerosis (MS), and other neurological conditions. While sensory retraining therapy has shown some benefits, there is no established method to restore tactile sensation following...

Published: 1/5/2022 | Inventor(s): Michael Kilgard

Keywords(s): Devices, Engineering & Physical Sciences, Internet of Things (IoT), Medical, Research Tools, Software, Therapeutics, Wireless

Category(s): Diagnostics, Healthcare, Medical Devices

Multiplexed Chip System for Analysis of Drug Activity in Cell Extracts

This technology uses multielectrode chips with DNA monolayers to analyze drug activity of DNA-damaging cancer treatments to inform therapeutic decisions for personalized medicine. Due to the unpredictability of cancer drugs, it is difficult to identify which therapy will work most effectively for each individual while producing minimal side effects....

Published: 4/26/2019 | Inventor(s): Jason Slinker, Dimithree Kahanda, David Boothman

Keywords(s): Assay, Biomarkers, Cell Lines, Devices, Engineering & Physical Sciences, Materials, Medical, Membrane, Microfluidics, Processes, Therapeutics

Category(s): Electronics, Diagnostics, Healthcare, Research Tools

Total Energy Shaping for Task-Invariant Control of Lower-Limb Exoskeletons

We present a total energy shaping control methodology for the development of portable lower-limb assistive exoskeletons and orthotic devices that help reduce the human’s effort and augment natural motion. Current robotic exoskeletons restrict joint motion to pre-defined position trajectories during gait rehabilitation; such methods aim to replicate...

Published: 5/20/2020 | Inventor(s): Robert Gregg, Ge Lv

Keywords(s): Biocompatible, Devices, Electronics, Engineering & Physical Sciences, Mechanical Systems, Medical Devices, Research Tools, Sensors & Controls, Signal Processing, Software, Therapeutics, Transportation, Wireless

Category(s): Robotics, Healthcare, Control Strategy

A Lower Limb Powered Orthosis for Improved Rehabilitation Training

Physical training is often needed for patients to relearn how to walk after a stroke, or other neurological damage. However, the frequency and availability of physical training are limited by finite medical resources: most lower-limb rehabilitation orthoses are stationary and only available in a limited number of clinical settings, due to their large...

Published: 5/20/2020 | Inventor(s): Robert Gregg, Hanqi Zhu

Keywords(s): Electronics, Engineering & Physical Sciences, Medical Devices, Motors, Research Tools, Sensors & Controls, Therapeutics

Category(s): Devices, Healthcare, Robotics, Mechanical Systems

Transient Optical Opening of the Blood-Brain Barrier by Laser Excitation of Plasmonic Nanoparticles

The blood-brain barrier (BBB) poses a low permeability to most drugs and poses a significant challenge to effective treatment of brain diseases. The BBB restricts the delivery of most drug molecules into the brain by tight junctions (TJs) that seal gaps between adjacent endothelial cells, displaying low permeability and high electrical resistance. Herein,...

Published: 4/26/2019 | Inventor(s): Zhenpeng Qin, Xiaoqing Li, Xiuying Li, Shashank Sirsi, Heather Hayenga, Edward Pan

Keywords(s): Biomarkers, Diagnostics, Drug Delivery, Engineering & Physical Sciences, Imaging, Materials, Medical, Research Tools, Therapeutics

Category(s): Biomedical, Nanotechnology, Healthcare

Virtual Body-Weight Support via Lower-Limb Exoskeleton

Summary:This is a novel control system for powered lower-limb exoskeletons (or orthoses) that provides body-weight support (BWS) for people who have sustained a stroke and other neurological injury. Patients are provided with BWS during conventional gait retraining to help them produce the coordinated muscle activities needed for walking. Although current...

Published: 5/20/2020 | Inventor(s): Robert Gregg, Ge Lv, Hanqi Zhu

Keywords(s): Biotechnology, Engineering & Physical Sciences, Life Sciences, Medical Devices, Motors, Research Tools, Sensors & Controls, Signal Processing, Therapeutics

Category(s): Electronics, Healthcare, Robotics, Control Strategy, Devices, Mechanical Systems

Amorphous Silicon Carbide Ultramicroelectrode Arrays for Neural Interfaces

The clinical ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response (FBR), which can lead to neuron damage and reduced reliability. Minimizing this tissue response is necessary for the development of implantable interfaces for studying neural...

Published: 4/26/2019 | Inventor(s): Stuart Cogan, Timothy Gardner

Keywords(s): Biocompatible, Electronics, Engineering & Physical Sciences, Implantable, Life Sciences, Materials, Medical, Sensors & Controls, Therapeutics

Category(s): Research Tools, Devices, Healthcare

Neurocase: Peripheral Nerve Electrode for Neural Recording and Stimulation

The ability to record and stimulate neural activity with implanted microelectrode arrays has been limited by the problems of insertion trauma and foreign body response, which can lead to neuron damage and reduced reliability of results. Minimizing such tissue responses is necessary to develop implantable interfaces for studying neural activity and even...

Published: 1/5/2022 | Inventor(s): Stuart Cogan, Atefeh Ghazavi, Alexandra Joshi-Imre

Keywords(s): Biocompatible, Biotechnology, Electronics, Engineering & Physical Sciences, Healthcare, Implantable, Life Sciences, Materials, Medical, Medical Devices, Therapeutics

Category(s): Biomedical, Devices, Research Tools

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