Search Results - assay

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System for Extracting Venous Pulsation and Respiratory Information from Photoplethysmographs

The University of Texas at Dallas presents a technique that addresses the inaccuracy of skin-mounted photoplethysmographic (PPG) biosensor measurements by separating the arterial and venous signals - enabling extraction of other medically-relevant features, including: respiration rate, heart rate, and SpO2. The effective removal of various motion artifacts...

Published: 4/26/2019 | Inventor(s): Mehrdad Nourani, Rasoul Yousefi

Keywords(s): 5G, Assay, Diagnostics, Electronics, Research Tools, Software, Wireless

Category(s): Healthcare, Software & Information Technology, Signal Processing, Medical Devices

Accurate and Motion-Tolerant Sensing of Arterial and Venous Pulsation for Wearable Photoplethysmographic (PPG) Biosensors

The University of Texas at Dallas presents a real-time, adaptive technique that provides robust signal enhancement against motion artifact for wearable photoplethysmographic (PPG) systems, enabling the reliable extraction of heart rate and oxygen saturation. Despite the benefits of using PPG biosensors, most of the useful information they capture...

Published: 4/26/2019 | Inventor(s): Mehrdad Nourani, Rasoul Yousefi

Keywords(s): 5G, Assay, Diagnostics, Electronics, Research Tools, Software, Wireless

Category(s): Healthcare, Medical Devices, Signal Processing, Software & Information Technology

Multiplexed Chip System for Analysis of Drug Activity in Cell Extracts

This technology uses multielectrode chips with DNA monolayers to analyze drug activity of DNA-damaging cancer treatments to inform therapeutic decisions for personalized medicine. Due to the unpredictability of cancer drugs, it is difficult to identify which therapy will work most effectively for each individual while producing minimal side effects....

Published: 4/26/2019 | Inventor(s): Jason Slinker, Dimithree Kahanda, David Boothman

Keywords(s): Assay, Biomarkers, Cell Lines, Devices, Engineering & Physical Sciences, Materials, Medical, Membrane, Microfluidics, Processes, Therapeutics

Category(s): Electronics, Diagnostics, Healthcare, Research Tools

Small Molecule Inhibitor of Forkhead Box Protein C2 (FOXC2): Therapeutic Candidate and Diagnostic Tool for Metastatic Cancers

The transcription factor Forkhead Box Protein C2 (FOXC2) is known to be necessary to initiate and maintain the epithelial-mesenchymal transition (EMT), which has been a hot target for therapeutic intervention against cancers. The overexpression of FOXC2 bestows cancer cells with metastatic and cancer stem cell (CSC)‐like phenotypes, i.e., higher motility,...

Published: 4/26/2019 | Inventor(s): Jiyong Lee, Maria Castaneda

Keywords(s): Assay, Biocompatible, Biomarkers, Chemistry, Drug Delivery, Healthcare, Imaging, Life Sciences, Medical, Molecular Biology, Nanotechnology, Research Tools, Therapeutics

Category(s): Biomedical, Diagnostics

Synthetic Binders of Breast Cancer Stem Cells

In recent decades, abundant research data has indicated the existence of cancer stem cells (CSCs), which represent a small, but significant, population among all cells within tumor tissues. These CSCs are mostly responsible for resistance to chemotherapy and radiation therapy, thereby becoming a root of tumor recurrence and metastasis. Several known...

Published: 4/26/2019 | Inventor(s): Jiyong Lee, Luxi Chen, Chao Long

Keywords(s): Assay, Biomarkers, Healthcare, Imaging, Life Sciences, Medical, Molecular Biology, Polymers, Research Tools, Therapeutics

Category(s): Biomedical, Diagnostics

Method for Measuring Carbon Nanotubes Taken-Up by a Plurality of Living Cells

Carbon nanomaterials (CNMs), including carbon nanotubes (CNTs) and graphene, are undergoing extensive research due to their diverse commercial applications and potential for biomedical uses. The global increase in the production of CNMs and incorporation into consumer products is cause for concern because of the consistent reports that CNMs can be toxic....

Published: 4/26/2019 | Inventor(s): Rockford Draper, Paul Pantano, Ru-Hung Wang, Carole Mikoryak

Keywords(s): Assay, Biotechnology, Carbon Nanomaterials, Carbon Nanotubes, Engineering & Physical Sciences, Healthcare, Imaging, Life Sciences, Materials, Microfluidics, Molecular Biology, Nanotechnology, Processes

Category(s): Research Tools

Portable Electrochemical Impedance System for Universal Molecular Diagnostics

Current methods of producing molecular diagnostic tools have many drawbacks, such as: the high-cost of fabrication, poor biodegradability, limited customizability, or issues with controlled fluid flow. Such problems have limited the ability to create portable detection devices for use in point-of-care settings that use environmentally-safe disposable...

Published: 4/26/2019 | Inventor(s): Shalini Prasad, Anjan Panneer Selvam

Keywords(s): Assay, Biocompatible, Biomarkers, Chemistry, Devices, Electronics, Engineering & Physical Sciences, Healthcare, Life Sciences, Medical, Medical Devices, Microfluidics, Molecular Biology

Category(s): Diagnostics